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In addition, ATOX1 functions as a copper-sensitive transcription factor through interactions with Sp1 and metal regulatory transcription factor 1, thereby affecting genes involved in the oxidative stress response and neuronal plasticity (40,41)

doi: 10.1016/j.semcancer.2017.06.001 102 YuHLeeHHerrmannABuettnerRJoveR

As IL-17A was positively linked to IgA while negatively correlating with disease severity markers (Figure 6), consistent with previous reports that IL-17A promoted protective IgA responses (Dann et al., 2015

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